A new Os,Rh bimetallic with O2 independent DNA cleavage and DNA photobinding with red therapeutic light excitation.

نویسندگان

  • Jing Wang
  • Samantha L H Higgins
  • Brenda S J Winkel
  • Karen J Brewer
چکیده

Many Ru and Os systems display photoactive (3)MLCT states. Systems activated by therapeutic window light in the absence of O(2) remain elusive. [(bpy)(2)Os(dpp)RhCl(2)(phen)](3+) photobinds and photocleaves DNA under red light in an oxygen independent manner, due to molecular design involving one Os chromophore coupled to a photoactive cis-Rh(III)Cl(2) moiety.

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عنوان ژورنال:
  • Chemical communications

دوره 47 35  شماره 

صفحات  -

تاریخ انتشار 2011